今晚上小白师姐为大家介绍蛋白组学与各个科研热点结合如何发表文章和基金,主要从外泌体、肠道菌群、蛋白修饰组学和与其它组学结合这四个方面展开,中间还会介绍面临纷繁复杂的各种技术该如何选择等关键问题,感兴趣的同学可以单击文末阅读原文进行报名。
上图是蛋白组学的通用流程
下面我们梳理了蛋白组学的经典综述,以飨各位。同样,文末是下载链接。
.多组学研究方法与疾病:Multi-omicsapproachestodisease.GenomeBiol.May05;8()Multipleomicsdatatypesandapproachestodiseaseresearch2.肿瘤激酶组学:Thekinome‘atlarge’incancerNat.Rev.CancerFeb;6(2)Driverproteinkinasesidentifiedbygenomicstudies.
Assignmentofdriverkinasestocorecellularpathwaysandprocesses3.蛋白组学与神经科学:APrimeronConceptsandApplicationsofProteomicsinNeuroscience.NeuronNov0;96(3)ComplexityofNeuroproteomicSamples
InvestigationofProtein-BasedInteractionsUsingNeuroproteomics
4.蛋白组学与心血管系统疾病和分子标志物发现:ProteomicsResearchinCardiovascularMedicineandBiomarkerDiscovery.J.Am.Coll.Cardiol.Dec27;68(25)
TheRoleofProteomicsintheSearchForBiomarkersandMechanismsOfAcquiredCardiovascularDiseases
5.蛋白组学与中药、天然产物:Targetidentificationofnaturalandtraditionalmedicineswithquantitativechemicalproteomicsapproaches.Pharmacol.Ther.06;62
Targetidentificationusingaffinitypurification-basedchemicalproteomicsapproaches
6.肾病蛋白组学标志物发现:Proteomicbiomarkersinkidneydisease:issuesindevelopmentandimplementation.NatRevNephrolApr;(4)Thetwomainroutesofproteomicbiomarkerdevelopment
7.蛋白互作组学:PredictingProtein-ProteinInteractionsfromtheMoleculartotheProteomeLevel.Chem.Rev.0427;6(8)
蛋白互作的各个数据库情况
8.蛋白组学的公共数据库:AGoldenAgeforWorkingwithPublicProteomicsData.TrendsBiochem.Sci.May;42(5)
下次小白师姐讲数据挖掘的时候还会讲。
9.可变剪接可能不是蛋白多样性的关键:AlternativeSplicingMayNotBetheKeytoProteomeComplexity.
IdentifyingTwoPeptidesfromtheSameSpectrum
0.质谱鉴定蛋白互作的问题和机遇:CharacterizingProtein-ProteinInteractionsUsingMassSpectrometry:ChallengesandOpportunities.TrendsBiotechnol.Oct;34(0)
ProteinPurificationStrategiesforMS-BasedPPIIdentification
下载链接:参地益肾口服液白癜风的治疗秘方
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